Asbestos industry regulation and mortality rates among the workers

Asbestos industry regulation and mortality rates among the workers

Most people are exposed to asbestos at work. Often through lack of proper safety procedures and links Some occupations are more dangerous than others. An interesting study is called, "A mortality among workers in an English asbestos factory" from Peto J, Doll R, SV Howard, LJ Kinlen and HC Lewinsohn - Br J Ind Med 1977, 34:169-173. Here is an extract: - (. Knox et al, 1968) "Abstract The last report on this cohort study of workers in an asbestos textile factory Showed little evidence of increased mortality among the workers who entered the plant after the implementation date 1932 had established the first Asbestos Industry Regulation (1931), but that no firm conclusions could be drawn as little carcinogenic effect would be expected for 20 years after the initial exposure. Additional 8 1/2 years follow-up has some asbestos related diseases in this latter group showed, albeit much less than for employees first exposed before 1933 Among the 963 employees first in 1933 or later mortality was suspended for carcinoma of the bronchus increased. (31 deaths; 19-3 for all lung cancer expected) and non-malignant respiratory diseases (35 deaths, 25-0 expected) and a further 5 deaths were pleural mesothelioma attributed to "Another interesting study is called," The Effects of cigarette smoke and asbestos on airway, vascular and mesothelial cell proliferation "by Sekhon H, J Wright, Churg A. - .. Department of Pathology, University of British Columbia, Canada - Int J Exp Pathol. December 1995, 76 (6) :411-8. Here is an excerpt: "Abstract - To determine whether exposure to both cigarette smoke and asbestos leads to increased cell proliferation, and whether pleura cell proliferation reflects the presence of fibers at or near the pleura, the rats of the air were exposed (control), daily cigarette smoke, a single intratracheal instillation of amosite asbestos, or a combination of smoke and asbestos. dividing cells were treated with bromodeoxyuridine (BrdU) labeled and the animals were killed after 1, 2, 7 or 14 days. both cigarette smoke and asbestos produced increases in the labeling index of the small airways wall, epithelial cells and pulmonary artery cells.'s small airways there was a brief clear positive synergistic interaction between these agents, but the synergy has not been seen in the vessels. cigarette smoke not to an increase in labeling of mesothelial cells or submesothelial cells while asbestos causes a persistent increase in mesothelial cell labeling. There was no correlation between the number of BrdU labeled mesothelial submesothelial cells and the number of fibers touching the pleura, or located within 180 microns of the pleura. We conclude that the combination of cigarette smoke and asbestos exposure produces a complex series of interactions, and has the potential to significantly increase cell proliferation in the parenchyma, an effect that may be important in both fibrogenesis and carcinogenesis. Unlike the decreasing effect of the time of a single dose of asbestos on cell proliferation in the small airways and container performs the same dose of asbestos maintained mesothelial cell proliferation, however, asbestos is the latter method is not correlated with the local accumulation of asbestos fibers "A third study is called," bodies, their formation, composition and character "of FD Pooley. -. Environmental Research - Volume 5, Issue 4, December 1972 Pages 363-379. Here is an excerpt:. "Abstract - Asbestos bodies were extracted from human lungs were examined under the electron microscope to determine their morphology and diffraction properties of the asbestos bodies from the lungs of persons exposed to the four types of commercial asbestos fibers, namely cocidolite extracts were , amosite, anthophyllite and chrysotile.Asbestos bodies were rarely found on the fibers is less than 10 micras in length and nearly always on the straight fibers. you were to occur less frequently on all four commercial grades of asbestos, but chrysotile. Properties the individual fibers were found to play a major role observed in determining the scope and frequency of body shapes. There seems to be no evidence to gradual formation of asbestos bodies found bodies.Asbestos, an important component that crystalline structurally similar extracts of ferritin from animal have been made ​​and human organs be beat .. The material that the asbestos body is definitely biological origin and corresponded exactly to the material in the medical literature defined as hemosiderin "If you found any of these excerpts helpful, please read this in its entirety