Dairy proteins caused aggressive breast cancer
New research suggests that a protein that triggers the production of breast milk in women may be a cause of aggressive breast cancer .
The discovery also could open up new possibilities in the treatment of the most common cancer in women and the most lethal .
Researchers in Australia and the United Kingdom found that ELF5 protein activates milk production in all cells of the breast , including cancer .
ELF5 active protein in cells exposed to cancer that later made into a more aggressive breast cancer .
" This discovery opens up new possibilities for healing treatments and to design new signs that can memprediki response to therapy , " said Professor Chris Ormandy of the Garvan Institute of Medical Research , Sydney .
Research by Ormandy and his team published in the journal PLoS Biology on Friday .
" Cancer cells can not respond appropriately to ELF5 , therefore these cells carry certain characteristics which make the disease becomes more aggressive and more resistant to the ongoing relief efforts , " Ormandy said .
Breast cancer is the most common cancer suffered by women , and the cause of death in the kelompol .
As many as 23 percent of the total cancer cases are breast cancer , and the disease also causes 14 percent of deaths in women .
To determine the proper treatment , the doctor must first determine whether a cancer has receptors for the hormones estrogen and progesterone in breast cancer cases make tumors grow .
Two-thirds of breast cancers are usually positive for estrogen receptors , which then require anti - hormonal therapy to reduce estrogen levels in patients , and blocking these hormones to grow cancer .
One third of the remaining cases of cancer was noted that women do not have receptors , which means they will not benefit from anti - hormonal therapy . Patients are usually given other treatments , such as chemotherapy .
The research team Ormandy discovered that the cancer has few ELF5 receptors , and vice versa .
" What we show in this study is that tumors with high ELF5 highly dependent on the protein to be able to evolve , and therefore if we can block the tumor 's supply ELF5 , then we can limit its growth , " Ormandy said .
He added , " If we can develop drugs that specifically target ELF5 , then it may be very useful for the women . "
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