HIV can begin to heal the radio immunotherapy
Scientists have found a new way to combat HIV infection based on the "murder" of radioactive radiation in cells infected with human immunodeficiency virus.
Scientists point out that visokoaktivna antiretroviral therapy (HAART), which is prescribed for people with HIV, only reduces the level of virus in the blood to very low values, but does not kill cells infected with the virus.
For the destruction of these cells, researchers decided to apply along with HAART radìoìmunoterapìû-technique developed to treat cancer.
It is based on the application that you create in vitro monoclonal antibodies, which are "prišivaêt′sâ" one or the other radioactive isotope. Such Molecular design of sighting attack only cancer cells and kill them by using radioactive radiation.
The scientists used a short-lived radìoìzotop bismuth-213, which "were not loaded with ' Polyclonal antibodies to one of the proteins that are located on the surface of infected HIV cells.
These antibodies, scientists added to blood samples taken in 15 people with HIV, and were receiving antiretroviral therapy. In the end died a considerable the number of cells infected with the virus, and neighboring healthy cells remained unharmed.
In addition, the researchers tested their technique on a laboratory model of central nervous system. Antibodies with isotope was successfully the team's artificial brain barrier through which does not penetrate the medications, which are not damaged it and killing the infected nerve cells.
The next step of scientists will become the clinical trials of radioisotope method for participation in HIV-patients.
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