Study on gene Reveals the origins of Cancer
A group of scientists managed to uncover the origins of the United Kingdom a number of the most common types of cancer. Scientists
based in Cambridgeshire, find the ' genetic ' signatures from more than
20 processes that alter the structure of DNA and in turn cause cancer.
This finding is considered crucial because it could encourage a better way in treating and preventing various types of cancer.
"(It)
is an important step to find processes that could encourage the
formation of cancer," said one of the researchers from the Wellcome
Trust Sanger Institute, Serena Nik Zainal-as reported by the Reuters
news agency.
The researchers analyzed the genome of cancer cases in humans 7.042 worldwide. The study also includes 30 types of cancer to see if they could find patterns, signatures, or the process of mutation.
As
a result, scientists find all cancer has two or more signatures-a
finding that shows the processes that work together when developing
cancer. They also find that different cancers have different number of mutation process anyway.
According to the researchers, the development of two mutation process melatari of ovarian cancer. While the six other mutations underlying developmental processes of liver cancer.
Then some of the signatures found in several types of cancer, while others are only found in one type. Of the 30 types of cancer, 25 of them had signatures from the process of mutations associated with aging.
Through
detailed analysis, said Nik-Zainal, people can begin to take advantage
of large amounts of information that is buried deep in the DNA of
cancer. For example, understanding how and why cancer appear.
In
the study, published in the journal Nature, the researchers also found
that a family of enzymes that could alter DNA structure, APOBECs, is
associated with more than half the cancers examined
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