A cup of coffee a day may protect against colon cancer and breast
According to the results of "nutrigenomics study of the effect of polyphenolic compounds from coffee on human tumor cells," conducted by the Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Barcelona, the daily consumption of a cup of coffee can modulate the immune system and protect against colon cancer and breast .
The data from the research is in addition to the existing scientific evidence about the protective role that moderate and regular consumption of coffee could play against some types of cancer .
To carry out this study in vitro cell models of colon and breast cancer were treated with concentrations of caffeic acid and chlorogenic acid equivalent to the daily intake of a cup of coffee as they had previous scientific evidence of the antioxidant power of these compounds polyphenolic coffee. The study authors found that the caffeic acid and chlorogenic and instant soluble coffee, also used in research, not only do not have a toxic effect on cells at concentrations corresponding to a cup of coffee a day, but even have an apparent protective nature to the genes involved in the immune response and cancer biology.
The study shows that these polyphenolic compounds coffee STAT5B modulate gene expression, which regulates the signaling pathway of prolactin, a hormone with immunoprotective nature in developing B lymphocytes With regard to cancer prevention, research shows that coffee can reduce the level of ATF2, a protein that increases cellular stress and promotes the growth of skin tumors.
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