How exposure to the asbestos cause mesothelioma pericardial?

How exposure to the asbestos cause mesothelioma pericardial?

Diagram of the Mesotelioma Pericardial
Pericardial mesothelioma is caused when asbestos is around the heart.
The causal relationship between exposure to asbestos and pericardial mesothelioma is not completely clear. Some researchers confirm that the pleural or peritoneal mesothelioma is caused primarily by exposure to asbestos, however, pericardial type is not completely definitive. Some patients with pericardial mesothelioma have a history of asbestos, although due to number of cases that exist throughout the world does not allow doctors to analyse effectively a relationship between the two. A study in 1982 found a history of exposure to asbestos in 3 of 15 times, and in 1994, the study reported that 4 of 15 cases analyzed were related to exposure to asbestos.

Asbestos fibres can to stay at the membranes pericardial bordering the heart. When this happens (such as with the lungs and the lining of the abdomen) the body begins to have difficulties to eliminate these fibers. These can be caught in membranes and a period of time long (in some cases up to 50 years) fibers can lead to the cell of the pericardium to pass through a series of changes that can result in cancer.

Once the cancer cells begin to multiply more quickly, their reproduction begins to be unstoppable. As continuous pericardial mesothelioma cancer grow, this leads to the widening of the pericardial membranes and eventually cause a tumor that develops. These changes in the pericardial membrane leading to the accumulation of fluid between the layers of the pericardium, which combined with the aforementioned widening, it puts pressure on the heart.

Diagnosis of Mesotelioma pericardial

To diagnose Mesothelioma pericardial, the patient's symptoms, medical history and current medical condition of the patient must be detailed thoroughly. Scans tests can help determine specifically where the tumor is located.

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A computed tomography scan (CT Scan) provides fairly accurate information about the town of peritoneum tumor, this is a tool quite used to make a diagnosis. Magnetic resonance imaging can also throw quite accurate results to determine the cancer. Pericardial tumors usually are not localized and tend to cover most of the heart. In later stages, this mesothelioma represents approximately half of the pericardial tumors.

The scan, a fairly advanced detection method that involves injecting radioactive material to help identify cell cancer, was used in at least one case of pericardial mesothelioma. Using this scan to detect the cancer, it is necessary to use a radio quite radioactive chemical gallium.

A biopsy may be more suitable to determine the point of origin of the cancer. This process requires removing some tissue or fluid in the pericardium followed by a laboratory test to confirm the presence of cancer.

Between 10 and 20 per cent of the cases of pericardial mesothelioma are diagnosed before the death of the patient. On the other hand, between 80 and 90 per cent of diagnosed cases are made after the death of the individual. Some of the problems associated with the diagnosis early pericardial mesothelioma is the low number of cases that affected patients and the symptoms that appear to be so delayed.

Treatment of the Mesotelioma Pericardial?

Available for patients with pericardial mesothelioma treatment options are limited since the layers covering are so close to the heart that any type of error during treatment can affect the heart as such. The majority of patients with this type of cancer are not eligible for any type of surgery, which is usually the most effective way of trafficking mesothelioma. However, there are very rare cases in which the cancer is diagnosed at an early stage and surgery may be performed in order to remove small tumors that have been localized. It should be taken into account that the risk of this disease is quite high due to its proximity to the heart, one of the most important organs in the human body.

If a patient is considered to be a good candidate for surgery, it will be treated with a pericardirectomia, a surgical procedure that involves removing part or all of the pericardium. This method can relieve pressure and relieve fluid, allowing it to continue operation itself. A pericardiocentesis is to remove excess fluid accumulated in the pericardium to relieve the pressure around the heart.

An option that is normally considered for trafficking mesothelioma chemotherapy but the clinical benefit seen in patients with this type of mesothelioma are minimal. Similarly, radiation therapy, which is considered one of the primary treatments for patients with pleural and peritoneal mesothelioma, is considered to be ineffective for those with pericardial mesothelioma cancer.

 Some palliative treatment is the most viable option in common, this simply try to minimize the pain and reduce the symptoms caused by the buildup of fluid in the pericardium. Essentially, palliative care can improve the quality of life of the patient to thus make you feel more comfortable. Palliative treatments include therapies that can relieve the pain and pressure around the heart, some examples are pericardiocentesis and use of analgesics.

Another treatment that removes excess fluid from the pericardial is known as fine needle aspiration. This palliative treatment is commonly used for patients with pleural mesothelioma, but it might be useful for certain patients with pericardial mesothelioma type.

Forecast Mesotelioma Pericardial?

The Outlook of most common life for those affected by Mesothelioma of the pericardium is less than that for patients with pleural or peritoneal mesothelioma. Around between 50 and 60 per cent of patients with mesothelioma pericardial die in the first six months of their diagnosis. However, this is not the case for everyone.

The hope for some patients with pericardial mesothelioma is that researchers who report positive results using surgical excision of localized tumors. In addition two patients reacted positively to the partial extraction of the pericardium and a patient came to life a year after treatment and lived for five years after it. Smaller and less impact benefits have been demonstrated with chemotherapy.

Like the other types of mesothelioma, a diagnosis early can give a more optimistic prognosis resulting in more options to treat the patient. This is extremely rare because the symptoms appear to measure that the disease progresses.