Stages of Mesothelioma - Butchart stage System - Prognostic factors - TNM staging system
Stages of Mesothelioma
The term stage is used to define the extent to which the cancer has proliferated. The stage of mesothelioma is done using images like MRI and determination strongly affects the patient's prognosis.
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Today the stage only exists for the most common form of mesothelioma, pleural. The stage is usually done using the Butchart system is based on tumor size giving the numbers 1, 2,3 and 4.
Butchart stage System
ButchartStage 1 : Cancer is located on one side of the pleural membrane and occasionally in the pericardium, lung diaphragm or that side.
Stage 2 : The cancer has spread to the chest and / or esophagus, both sides of the pleura or the heart. Cancer cells can be present in the lymph nodes.
Stage 3 : The cancer has spread to the peritoneum through the diaphragm. Cancer can be found in lymph nodes located outside the lung cavity.
Stage 4 : The cancer has widely expanded.
TNM staging system
The newly developed TNM system is based on tumor (T), lymph nodes (L) and level of metastasis (M) As the Butchart system, the numbers 1 to 4 are used to identify each stage.
Stage 1 : The cancer is located in a part of the pleural membrane and occasionally in the pericardium, or diaphragm on the lung on that side.
Stage 2 : The cancer will be located in the pericardium, mediastinum, diaphragm and down but remains localized on one side of the chest. The cancer has yet been extended to the nodules or nodes or other sites.
Stage 3 : The cancer has spread to the heart, esophagus, muscles of the chest wall, ribs and other organs located on the same side as the tumor. This phase also includes those mesotheliomas have spread to the lymph nodes but localized manner similar fashion to the second stage.
Stage 4 : The cancer has spread to the lymph nodes located behind the peritoneal primary tumor or pleural membrane, or other organ in the abdomen or neck. The stage 4 includes those cancers in which there are already metastases.
The Butchart system is still the most accepted system for determining stages of pleural mesothelioma Knowing the stage of the tumor is necessary to determine the patient's prognosis and determine the appropriate treatment.
Prognostic factors
Mesothelioma factorsThere is widespread awareness of the risks surrounding mesothelioma compared to other types. This is due to the fact that no good studies since it is usual for this type of disease. It is known that the younger the patient, the better your health, the better prognosis may have.
Of the three forms of mesothelioma, epithelial mesothelioma is best prognosis is, biphasic mesothelioma being the second in terms of severity and fibrosarcomatoide the favorable outcome is worse.
References:
Doherty, Gerard M. (2010.) Current Diagnosis and Treatment Surgery . 13th ed.
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